Electrophoresis buffers are critical to the successful separation and analysis of nucleic acids and proteins. These pH-stabilized solutions ensure consistent ionic strength and minimize variability, supporting sharp band resolution and accurate migration in gel-based techniques.
Maintains stable pH and conductivity for reproducible separation
Supports DNA, RNA, and protein workflows with trusted formulations like TAE, TBE, and SDS-containing buffers
Compatible with agarose and polyacrylamide gels across a range of molecular weight targets
Whether you're running routine DNA gels or high-resolution SDS-PAGE, our electrophoresis buffers deliver reliable performance batch after batch.
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Frequently Asked Questions
What are electrophoresis buffers used for?
Electrophoresis buffers create the ionic environment needed for the migration of charged molecules, such as DNA, RNA, or proteins, through a gel matrix during electrophoresis.
What’s the difference between TAE and TBE buffer?
TAE (Tris-acetate-EDTA) offers faster migration and is ideal for downstream gel extraction or enzymatic applications. TBE (Tris-borate-EDTA) provides better resolution for small fragments and maintains buffering capacity over longer runs.
How do I choose the right electrophoresis buffer?
Buffer choice depends on the type of molecule (DNA, RNA, protein), gel type, desired resolution, and compatibility with downstream recovery or enzymatic steps.