Citrate Phosphate Buffer (Mcilvaine Buffer, pH 4.0)

The Citrate-Phosphate buffer, also known as Mcllvaine Buffer, is composed of citric acid and sodium phosphate dibasic generating a pH range of 3.0-8.0. This buffer type can be used in various applications, including histology, medical diagnostics, immunohistochemistry, and molecular biology. By carefully adjusting the concentration of citrate ions and phosphate ions, optimal buffering capacity can be achieved, providing a controlled environment for sensitive biochemical processes.